Matthijs Kox Selected Research

Biomarkers (Surrogate Marker)

2/2024	Myeloid-Derived Suppressor-like Cells as a Prognostic Marker in Critically Ill Patients: Insights from Experimental Endotoxemia and Intensive Care Patients.
12/2023	Inflammatory biomarkers to predict the prognosis of acute bacterial and viral infections.
4/2022	The value of bioactive adrenomedullin and dipeptidyl peptidase 3 to predict short-term unfavourable outcomes after cardiac surgery: A prospective cohort study.
1/2022	Targeted proteomics identifies circulating biomarkers associated with active COVID-19 and post-COVID-19.
1/2021	Dysregulated Innate and Adaptive Immune Responses Discriminate Disease Severity in COVID-19.
1/2021	Dexamethasone and tocilizumab treatment considerably reduces the value of C-reactive protein and procalcitonin to detect secondary bacterial infections in COVID-19 patients.
1/2021	The Association of TSH and Thyroid Hormones With Lymphopenia in Bacterial Sepsis and COVID-19.
12/2020	Longitudinal Multi-omics Analyses Identify Responses of Megakaryocytes, Erythroid Cells, and Plasmablasts as Hallmarks of Severe COVID-19.
10/2020	Biomarkers for antimicrobial stewardship: a reappraisal in COVID-19 times?
1/2020	Proenkephalin Compared to Conventional Methods to Assess Kidney Function in Critically Ill Sepsis Patients.

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Matthijs Kox Research Topics

Disease

47	Inflammation (Inflammations) 04/2024 - 10/2009
44	Sepsis (Septicemia) 04/2024 - 03/2007
35	Endotoxemia 02/2024 - 09/2009
23	COVID-19 12/2023 - 01/2020
21	Critical Illness (Critically Ill) 02/2024 - 10/2007
13	Infections 02/2024 - 03/2014
12	Septic Shock (Toxic Shock Syndrome) 04/2024 - 07/2013
6	Hypoxia (Hypoxemia) 01/2021 - 05/2014
6	Wounds and Injuries (Trauma) 08/2018 - 01/2015
3	Necrosis 12/2023 - 01/2022
3	Bacterial Infections (Bacterial Infection) 12/2023 - 01/2017
3	Overweight 04/2023 - 01/2021
3	Pneumonia (Pneumonitis) 01/2023 - 01/2012
3	Lymphopenia (Lymphocytopenia) 10/2021 - 12/2019
2	Obesity 04/2023 - 01/2023
2	Body Weight (Weight, Body) 01/2023 - 09/2011
2	Neoplasms (Cancer) 01/2023 - 01/2022
2	Shock 01/2023 - 01/2016
2	Acute Kidney Injury (Acute Renal Failure) 04/2022 - 01/2021
2	Hyperventilation 12/2021 - 05/2014
2	Coinfection 10/2021 - 01/2021
2	Fever (Fevers) 12/2020 - 01/2019
2	Anemia 01/2015 - 10/2014
2	Familial Cerebral Amyloid Angiopathy 02/2010 - 02/2009
2	Cerebral Amyloid Angiopathy (Congophilic Angiopathy) 02/2010 - 02/2009
2	Alzheimer Disease (Alzheimer's Disease) 02/2010 - 02/2009
1	Virus Diseases (Viral Diseases) 12/2023
1	Disease Progression 08/2023
1	Fibrosis (Cirrhosis) 08/2023

Drug/Important Bio-Agent (IBA)

34	CytokinesIBA 10/2023 - 01/2011
17	Biomarkers (Surrogate Marker)IBA 02/2024 - 01/2011
16	EndotoxinsIBA 02/2024 - 07/2011
12	LipopolysaccharidesIBA 04/2024 - 08/2011
11	Interleukin-10 (Interleukin 10)IBA 03/2023 - 01/2011
8	Norepinephrine (Noradrenaline)FDA LinkGeneric 01/2022 - 01/2016
8	Interleukin-6 (Interleukin 6)IBA 01/2021 - 02/2009
7	Interleukin 1 Receptor Antagonist Protein (Anakinra)FDA Link 03/2023 - 01/2011
7	AdrenomedullinIBA 01/2019 - 12/2014
6	InterleukinsIBA 03/2023 - 01/2018
5	alanyl-glutaminyl-glycyl-valineIBA 01/2021 - 01/2018
5	enibarcimabIBA 01/2019 - 01/2018
4	Dexamethasone (Maxidex)FDA LinkGeneric 08/2023 - 02/2009
4	Interleukin-8 (Interleukin 8)IBA 03/2023 - 01/2011
4	Proteins (Proteins, Gene)FDA Link 01/2022 - 05/2013
4	HLA-DR Antigens (HLA-DR)IBA 01/2020 - 03/2014
4	Adenosine (Adenocard)FDA LinkGeneric 07/2018 - 09/2012
3	Fatty Acid-Binding ProteinsIBA 03/2023 - 02/2015
3	Ferritins (Ferritin)IBA 01/2023 - 12/2020
3	Interferon-gamma (Interferon, gamma)IBA 10/2021 - 03/2014
3	C-Reactive ProteinIBA 10/2021 - 01/2021
3	Oxygen (Dioxygen)IBA 10/2021 - 11/2015
3	Phenylephrine (Neo-Synephrine)FDA LinkGeneric 03/2021 - 01/2018
3	InterferonsIBA 12/2020 - 04/2016
3	Interleukin-1 Receptors (Interleukin 1 Receptor)IBA 01/2020 - 01/2018
3	Vasopressins (Vasopressin)IBA 01/2020 - 01/2018
3	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 01/2020 - 01/2018
3	Hormones (Hormone)IBA 01/2019 - 10/2017
3	HepcidinsIBA 01/2019 - 10/2014
3	Escherichia coli endotoxinIBA 01/2017 - 01/2014
3	Mitochondrial DNA (mtDNA)IBA 01/2017 - 01/2016
2	AdiponectinIBA 04/2023 - 01/2023
2	ResistinIBA 04/2023 - 01/2023
2	AdipokinesIBA 04/2023 - 01/2023
2	LeptinIBA 04/2023 - 01/2023
2	Complement System Proteins (Complement)IBA 01/2023 - 01/2022
2	IceIBA 01/2023 - 05/2014
2	EnzymesIBA 01/2023 - 01/2020
2	Angiotensin IIIBA 01/2022 - 01/2021
2	VaccinesIBA 04/2021 - 12/2015
2	Messenger RNA (mRNA)IBA 01/2021 - 01/2017
2	ProcalcitoninIBA 01/2021 - 01/2011
2	RNA (Ribonucleic Acid)IBA 01/2021 - 01/2021
2	Adrenal Cortex Hormones (Corticosteroids)IBA 12/2020 - 07/2013
2	CreatinineIBA 01/2020 - 01/2016
2	Iohexol (Omnipaque)FDA Link 01/2020 - 01/2020
2	Aspirin (Acetylsalicylic Acid)FDA LinkGeneric 01/2019 - 01/2017
2	Chorionic Gonadotropin (Human Chorionic Gonadotropin)FDA LinkGeneric 01/2019 - 01/2018
2	GlucansIBA 01/2019 - 11/2016
2	Peptides (Polypeptides)IBA 01/2019 - 01/2018
2	Toll-Like Receptors (Toll-Like Receptor)IBA 01/2017 - 11/2014
2	Epinephrine (Adrenaline)FDA LinkGeneric 04/2016 - 05/2014
2	DNA (Deoxyribonucleic Acid)IBA 04/2016 - 01/2016
2	IronIBA 10/2014 - 03/2014
2	GlucocorticoidsIBA 01/2014 - 09/2009
2	Hydrocortisone (Cortisol)FDA LinkGeneric 06/2012 - 01/2011
2	Amyloid beta-PeptidesIBA 02/2010 - 02/2009
1	EpitopesIBA 04/2024
1	Peptide Hydrolases (Proteases)FDA Link 12/2023
1	Dipeptidyl-Peptidases and Tripeptidyl-PeptidasesIBA 12/2023
1	Prednisone (Sone)FDA LinkGeneric 08/2023

Therapy/Procedure

17	Therapeutics 02/2024 - 06/2013
8	Intravenous Administration 01/2023 - 06/2012
6	Immunotherapy 10/2021 - 06/2013
6	Artificial Respiration (Mechanical Ventilation) 01/2021 - 01/2012
5	Precision Medicine 12/2023 - 01/2017
5	Length of Stay 08/2023 - 02/2014
4	Critical Care (Surgical Intensive Care) 02/2024 - 06/2013
3	Meditation 04/2016 - 06/2012
2	Immunomodulation 01/2016 - 01/2014
2	Vagus Nerve Stimulation 06/2015 - 01/2012